Irradiación gamma aplicada a la síntesis de nanopartículas de selenio y su influencia en las propiedades fisicoquímicas.

Autores/as

  • Guilherme Henrique Domingos de Franco Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Conceptualización
    • Redacción - revisión y edición
    • Investigación
    • Metodología
    • Análisis formal
    • Visualización
    • Curación de datos
  • Thayna Felizardo dos Santos Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Investigación
    • Redacción - revisión y edición
    • Análisis formal
    • Curación de datos
    • Visualización
  • Luciana Mara Costa Moreira Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Investigación
    • Redacción - revisión y edición
    • Análisis formal
  • Alline Gomes Pereira Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Investigación
    • Análisis formal
    • Redacción - revisión y edición
  • Luanai Graziele Luquini Gerolis Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Investigación
    • Análisis formal
    • Redacción - revisión y edición
  • Maria Jose Neves Centro de Desenvolvimento da Tecnologia Nuclear image/svg+xml
    • Conceptualización
    • Metodología
    • Supervisión
    • Redacción - borrador original
    • Redacción - revisión y edición

DOI:

https://doi.org/10.15392/2319-0612.2026.3078

Palabras clave:

Irradiación gamma, Química verde, Caracterización de nanopartículas, Nanopartículas de selenio

Resumen

El selenio, un micronutriente esencial en pequeñas cantidades, presenta numerosos efectos beneficiosos en organismos como humanos, plantas y bacterias. Sin embargo, la relación entre el selenio y los organismos vivos es compleja debido a su estrecho rango de acción, que puede variar de beneficioso a perjudicial dependiendo de la concentración. Las nanopartículas de selenio (SeNPs) muestran un gran potencial debido a su reconocida biocompatibilidad, biodisponibilidad y baja toxicidad. No obstante, antes de considerar cualquier aplicación potencial, los parámetros fisicoquímicos de las SeNPs — como tamaño, forma, composición, estado de agregación y carga superficial — deben caracterizarse cuidadosamente, ya que la metodología de síntesis puede influir en su toxicidad. En el presente estudio utilizamos un método radiolítico, empleando radiación de ⁶⁰Co, para sintetizar SeNPs y posteriormente evaluamos detalladamente sus parámetros fisicoquímicos.

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Biografía del autor/a

  • Guilherme Henrique Domingos de Franco, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Master’s degree in Radiation, Minerals and Materials Science and Technology from the Center for the Development of Nuclear Technology (CDTN). Holds a Bachelor’s degree in Radiologic Technology from the Federal University of Minas Gerais (UFMG).

    He is currently a Ph.D. student in Radiation, Minerals and Materials Science and Technology at the Center for the Development of Nuclear Technology (CDTN), working in the same research area.

  • Thayna Felizardo dos Santos, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Master’s degree in Radiation Science and Technology (CTRA) from the Center for the Development of Nuclear Technology (CDTN). Holds a Bachelor’s degree in Biomedicine from Centro Universitário de Belo Horizonte (2019).

  • Luciana Mara Costa Moreira, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Bachelor’s degree in Biological Sciences with an emphasis in Environmental Management from the Pontifical Catholic University of Minas Gerais (2004); a Master’s degree in Radiation Science and Technology – Concentration Area: Nuclear Techniques in Health and Biology – from the Center for the Development of Nuclear Technology (2007); and a Ph.D. (2011) and postdoctoral training (2013) in Microbiology from the Federal University of Minas Gerais.

    Area of expertise and research: Microbiology, with emphasis on microbial biochemistry, oxidative stress, free radicals, probiotics, biochemical effects caused by heavy metals, and apoptosis and fluorescence techniques for the determination of oxidative damage.

  • Alline Gomes Pereira, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Ph.D. and a Master’s degree in Radiation, Minerals and Materials Science and Technology from the Center for the Development of Nuclear Technology (CDTN). Holds a Bachelor’s degree in Biological Sciences (Licensure)from the Federal University of Minas Gerais (2009–2013).

    Has experience in Biochemistry and Immunology, with emphasis on Immunology, focusing on the immunology of inflammatory bowel diseases; and in Pathology, particularly the immunology and histopathology of dogs naturally infected with Leishmania (Leishmania) chagasi; as well as in Microbiology, with emphasis on bioremediation and cellular responses.

  • Luanai Graziele Luquini Gerolis, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Ph.D. and a Master’s degree in Radiation, Minerals and Materials Science and Technology from the Center for the Development of Nuclear Technology (2019). Holds a Bachelor’s degree in Biological Sciences from the Federal University of Rio de Janeiro (2008) and a specialization in Environmental Management from the SENAC-MG Graduate Program Center (2012).

    Has experience in green chemical synthesis of selenium nanoparticles, nanomaterial characterization for bioapplications, investigation of organic compounds present in green tea responsible for nanoparticle reduction, evaluation of the antioxidant activity of green tea, and gamma irradiation studies.

  • Maria Jose Neves, Centro de Desenvolvimento da Tecnologia Nuclear

    Holds a Bachelor’s degree in Biological Sciences (Medical Modality) from the University of São Paulo (1982), a Master’s degree in Sciences (Human Physiology) from the University of São Paulo (1986), a Ph.D. in Sciences (Human Physiology) from the University of São Paulo (1991), and completed a postdoctoral fellowship at the Katholieke Universiteit Leuven (1994).

    Currently serves as a Senior Researcher at the National Nuclear Energy Commission (CNEN).

    Has experience in Biochemistry, with emphasis on Microbial Biochemistry, working mainly on the following topics: heat shock, trehalose, glycogen, thermotolerance, trehalose-6-phosphate synthase, and trehalase.

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Publicado

2026-10-23

Declaración de disponibilidad de datos

Los datos que respaldan los resultados de este estudio están disponibles con el autor de correspondencia previa solicitud razonable. Los conjuntos de datos incluyen las mediciones experimentales obtenidas mediante análisis de DLS, UV–Vis, SEM, TEM, XRD y EDS utilizados en la caracterización de nanopartículas de selenio.

   

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