Perfomance analysis of a small animal PET scanner using 68Ga Isotope

Autores

  • Victória Garcia Moreira Universidade Federal de Minas Gerais UFMG, Faculdade de Medicina, Departamento de Anatomia e Imagem
  • Anna Clara Moreira Silva Universidade Federal de Minas Gerais UFMG, Faculdade de Medicina, Departamento de Anatomia e Imagem
  • Rodrigo Modesto Gadelha Gontijo Universidade Federal de Minas Gerais image/svg+xml
  • Andréa Vidal Ferreira Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN 31.270-901, Belo Horizonte, Minas Gerais, Brazil

DOI:

https://doi.org/10.15392/2319-0612.2025.2844

Palavras-chave:

PET, galium-68, Image Quality

Resumo

In recent years, the use of PET scanners for small animals in preclinical research has been growing in Brazil, due to this fact it is essential to have a quality assurance program to ensure the good performance of these scanners or indicate the need for corrective maintenance. In 2008, the National Association of Electrical Equipment Manufacturers (NEMA) in the USA published a document that proposes the following tests to ensure quality control: uniformity, spill-over ratio, and recovery coefficients. Thus, the objective of this work was to evaluate the image quality of the PET scanner for small animals LabPET SOLO 4 using the isotope Gallium-68. The results revealed that the use of the isotope 68Ga was quite different from standard tests using 18F. The project provided us with a comprehensive understanding of the functioning of the PET scanner when employing the radionuclide 68Ga. This evaluation is of crucial relevance for application in laboratories, especially in the quantitative analysis of PET images and in the planning of preclinical studies

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Referências

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[3] NEMA - National Electrical Manufacturers Association. Performance Measurements of Small Animal Positron Emission Tomographs; Rosslyn VA, Standards Publication NU 4-2008 (2008).

[4] Gontijo, R.M.G., “Image quality evaluation of a small animal PET scanner,” Brazilian Journal of Radiation Sciences, vol. 08-01, pp. 1–13 (2020).

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[7] Gontijo, R.M.G.; Ferreira, A.V.; SILVA, J.B.; LEWER, M. H. M. Estudo dos parâmetros de reconstrução em imagens MicroPET. In: XII Congresso SBBN, 2017, São Paulo. XII Congresso SBBN, (2017).

[8] Gontijo, R.M.G., “Image quality evaluation of a small animal PET scanner,” Brazilian Journal of Radiation Sciences, vol. 08-01, pp. 1–13 (2020).

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[12] National Institute of Standards and Technology, Available in: https://www.nist.gov/pmL/radiation-dosimetry-data. (2025).

Publicado

27-06-2025

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Como Citar

Perfomance analysis of a small animal PET scanner using 68Ga Isotope. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 13, n. 2, p. e2844, 2025. DOI: 10.15392/2319-0612.2025.2844. Disponível em: https://bjrs.org.br/revista/index.php/REVISTA/article/view/2844. Acesso em: 17 jul. 2025.