Parameters for Validating a Spectrometric System with Itinerant NaI(Tl) in the Activimeter Calibration
DOI:
https://doi.org/10.15392/2319-0612.2025.2810Palabras clave:
NaI(Tl), method validations, performance indicator parameters, activimeter calibrationsResumen
In radiopharmaceutical production centers and nuclear medicine services, short half-life radionuclides are essential. They have been used as radiotracers since their use increased significantly and aroused the interest of national metrology laboratories, which are responsible for providing traceability to radioactive standards. Therefore, knowledgement of the activity of administered radiopharmaceuticals must be obtained accurately. However, their short half-lives prevent the provision of traceability. To overcome these obstacles, an itinerant system based on a NaI(Tl)-type scintillator detector is being developed at the National Laboratory for Ionizing Radiation Metrology (LNMRI). This work aims to show the schematic arrangement of the system developed to calibrate activimeters, as well as the tests and experimental comparisons carried out in this study using performance indicator parameters to characterize and validate the itinerant NaI(Tl) detection system in the calibration of activimeters.
Descargas
Referencias
[1] IAEA, Quantitative Nuclear Medicine Imaging: Concepts, Requirements and Methods, International Atomic Energy Agency, Human Health Reports No 9, 2014.
[2] SAHA, G. B., Fundamentals of Nuclear Pharmacy. Fifth Edition. Springer, 2004.
[3] MICHOTTE, C.; NONIS, M.; ARENILLAS, P.; CERUTTI, G.; DA SILVA, C. J.; CRUZ, P. A. L.; MOREIRA, D. S.; IWAHARA, A.; DELGADO, J. U.; POLEDNA, R.; DA SILVA, R. L.; DE OLIVEIRA, A. E.; GOMES, R. S. Activity measurements of the radionuclide 99mTc for the CNEA, Argentina and the LNMRI/IRD, Brazil in the ongoing comparison BIPM.RI(II)-K4.Tc-99m, Metrologia (Online), v. 50, p. 06023-06023, 2013.
[4] ISO/20042, Measurement of radioactivity — Gamma-ray emitting radionuclides — Generic test method using gamma-ray spectrometry, 2019.
[5] AZEREDO, D. A.; DELGADO, J.U.; OLIVEIRA, A.E. Viabilidade para implantação de um sistema itinerante de referência para medição de radiofármacos no LNMRI. CBMRI, Rio de Janeiro, 2020.
[6] CHERRY, S.R.; SORENSON, J.A. PHELPS, M.E., 2012, Physics in nuclear medicine, 4th ed., Philadelphia, Elsevier, 2020.
[7] ISO/17025, Requisitos gerais para a competência de laboratórios de ensaio e calibração. 3° edição, ABNT NBR, Rio de janeiro, RJ. ISBN:978-85-07-07368-0, 2017.
[8] Osprey, Universal Digital MCA Tube Base, 7066438E. User’s Manual, 2012.
[9] CACAIS, F.L.; DELGADO, J.U.; LOAYZA, V. M. Uncertainty evaluation of a modified elimination weighing for source preparation, Brazilian Congress on Metrology, IOP Conf. Series: Journal of Physics: Conf. Series 975 (2018) 012057, doi :10.1088/1742-6596/975/1/012057, 2017.
[10] VIM, Vocabulário Internacional de Metrologia: Conceitos fundamentais e gerais e termos associados (VIM 2012). Duque de Caxias, RJ: INMETRO, 94 p, 2012.
[11] ISO 11929, Determination of the characteristic limits (decision threshold, detection limit and limits of the confidence interval) for measurements of ionizing radiation — Fundamentals and application, 2019.
Descargas
Publicado
Número
Sección
Licencia
Derechos de autor 2025 Dayana Azeredo Conceição, José Ubiratan Delgado, Octavio Luiz Trindade Filho
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Licencia: los artículos de BJRS tienen una licencia internacional Creative Commons Attribution 4.0, que permite el uso, el intercambio, la adaptación, la distribución y la reproducción en cualquier medio o formato, siempre que se otorgue el crédito correspondiente al autor o autores originales y a la fuente, proporcione un enlace a la licencia Creative Commons e indique si se realizaron cambios. Las imágenes u otros materiales de terceros en el artículo están incluidos en la licencia Creative Commons del artículo, a menos que se indique lo contrario en una línea de crédito al material. Si el material no está incluido en la licencia Creative Commons del artículo y su uso previsto no está permitido por la regulación legal o excede el uso permitido, el autor deberá obtener el permiso directamente del titular de los derechos de autor. Para ver una copia de esta licencia, visite http://creativecommons.org/licenses/by/4.0/
