Image quality assessment using NEMA NU 4/2008 standards in small animal PET scanner

Autores/as

  • Rodrigo Modesto Gadelha Gontijo Universidade Federal de Minas Gerais image/svg+xml
  • Andréa Vidal Ferreira Center of Nuclear Technology Development (CDTN/CNEN);
  • Juliana Batista Silva Center of Nuclear Technology Development (CDTN/CNEN);
  • Marcelo Henrique Mamede Center of Nuclear Technology Development (CDTN/CNEN); Federal University of Minas Gerais (UFMG)

DOI:

https://doi.org/10.15392/bjrs.v7i2A.580

Palabras clave:

Image Quality, Positron Emission Tomography, NEMA.

Resumen

In Brazil, there are few microPET in use and a quality control protocols standardization are needed to harmonize their use in the research field. Thus, the purpose of this study is to characterize the image quality performance of the microPET scanner (LabPET 4, GE healthcare Technologies, Waukesha, WI) using the NEMA NU 4/ 2008 standards and specific phantom. The NEMA image-quality (IQ) phantom consists of 3 different regions to analyze distinct characteristics: image noise (%SD), expressed as percentage SD in a uniform region (%SD), recovery coefficient (RC) and Spill-over (SOR) in air and water. The IQ phantom was filled with 18F-FDG calibrated at the beginning of acquisition, placed in the center of the field-of-view (FOV) and measured with the typical whole body imaging protocol. The images were reconstructed with different reconstruction methods (FBP-2D; MLEM-3D and OSEM-3D); with and without high resolution (HR) when possible. The results were compared. The LabPET 4 system produces appropriate image and with performance according to the literature. The present study is an initial step to verify the NEMA NU 4/2008 use in the Brazilian scenario for further standardization.

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Biografía del autor/a

  • Rodrigo Modesto Gadelha Gontijo, Universidade Federal de Minas Gerais

    Radiopharmaceuticals Research and Production Unit, Center of Nuclear Technology Development (CDTN/CNEN);

     Department of Anatomy and Imaging, Federal University of Minas Gerais (IMA/UFMG)

  • Andréa Vidal Ferreira, Center of Nuclear Technology Development (CDTN/CNEN);

    Radiopharmaceuticals Research and Production Unit, Center of Nuclear Technology Development (CDTN/CNEN);

     Department of Anatomy and Imaging, Federal University of Minas Gerais (IMA/UFMG).

  • Juliana Batista Silva, Center of Nuclear Technology Development (CDTN/CNEN);

    Radiopharmaceuticals Research and Production Unit, Center of Nuclear Technology Development (CDTN/CNEN);

  • Marcelo Henrique Mamede, Center of Nuclear Technology Development (CDTN/CNEN); Federal University of Minas Gerais (UFMG)

    Radiopharmaceuticals Research and Production Unit, Center of Nuclear Technology Development (CDTN/CNEN);

     Department of Anatomy and Imaging, Federal University of Minas Gerais (IMA/UFMG)

Referencias

YAO R.; LECOMTE R.; CRAWFORD E. Small-Animal PET: What is it, and why do we need it? Journal of Nuclear Medicine Technology. 2011. Vol. 40 nº3, pp.157-165.

NEMA - National Electrical Manufacturers Association. Performance Measurements of Small Animal Positron Emission Tomographs. Rosslyn VA; 2008 Standards Publication NU 4-2008.

GE Healthcare Technologies, Triumph Service Guide Technical Publication. Revision Draft 6, Copyright. Available at: <http://www.gehealthcare.com>. 2011.

TRETRAULT M. A., et al. System architecture of the LabPET small animal PET scanner. IEEE Transactions on Nuclear Science, 2008. Vol.55, pp. 2546-2550.

FONTAINE R., et al. The hardware and signal processing architecture of LabPETTM, a small animal APD-based digital PET scanner. IEEE Transactions on Nuclear Science, February 2009. Vol. 56, pp. 3-9.

DISSELHORST J. A., et al. Image-Quality Assessment for several Positron Emitters using the NEMA NU 4-2008 Standards in the Siemens Inveon Small-Animal PET Scanner. The Journal of Nuclear Medicine. April 2010. Vol. 51 nº4, pp. 610-617.

ZAIDI H. and RATIB O. NEMA NU-04-based Performance Characteristics of the LabPET-8TM Small Animal PET Scanner. 2001. IEEE Nuclear Science Symposium Conference Record. pp. 3654-3660.

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Publicado

2019-02-07

Número

Vol. 7 Núm. 2A (Suppl.) (2019): ENAN 2017

Sección

The Meeting on Nuclear Applications (ENAN)

Licencia

Derechos de autor 2021 Brazilian Journal of Radiation Sciences (BJRS)

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.

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Cómo citar

Image quality assessment using NEMA NU 4/2008 standards in small animal PET scanner. Brazilian Journal of Radiation Sciences (BJRS), Rio de Janeiro, Brazil, v. 7, n. 2A (Suppl.), 2019. DOI: 10.15392/bjrs.v7i2A.580. Disponível em: https://bjrs.org.br/revista/index.php/REVISTA/article/view/580. Acesso em: 16 jul. 2025.