Dosimetry for FLASH Radiotherapy: A review of dosimetric systems

Karoline Feitoza Suzart; Maria da Penha Albuquerque Potiens

doi:10.15392/2319-0612.2024.2620

Autores

Karoline Feitoza Suzart Instituto de Pesquisas Energéticas e Nucleares https://orcid.org/0000-0003-2116-7435 (não autenticado)
Maria da Penha Albuquerque Potiens Instituto de Pesquisas Energéticas e Nucleares https://orcid.org/0000-0002-4049-6720 (não autenticado)

DOI:

https://doi.org/10.15392/2319-0612.2024.2620

Palavras-chave:

radioterapia FLASH, revisão de literatura, sistemas dosimétricos

Resumo

A radioterapia FLASH (FLASH-RT) é uma abordagem promissora para o tratamento do câncer, caracterizada pela administração de altas doses de radiação em um curto período de tempo, em frações de segundos. Para demonstrar o efeito FLASH, são necessárias doses únicas elevadas de radiação administradas em tempos muito curtos através de um número limitado de pulsos. Estudos anteriores relataram que o tratamento FLASH-RT pode resultar em aumento da sobrevivência celular em comparação com a radioterapia convencional. Este artigo tem como objetivo realizar uma pesquisa bibliográfica abrangente sobre dosimetria em radioterapia FLASH, uma técnica emergente e promissora no campo da radioterapia. Serão discutidos alguns dos dosímetros mais utilizados em estudos recentes para radioterapia FLASH, incluindo câmaras de ionização, detectores de diamante, filmes radiocrômicos, filmes radiocrômicos EBT3 e dosímetros termoluminescentes. Serão analisados os principais parâmetros de dosimetria utilizados nos tratamentos radioterápicos FLASH, com ênfase nas características e aplicabilidade dos diferentes tipos de dosímetros utilizados.

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