Quality control of small animal PET scanner: The Brazilian Scenario

Authors

  • Rodrigo Modesto Gadelha Gontijo Federal University of Minas Gerais. UFMG https://orcid.org/0000-0001-6479-3087
  • Andréa Vidal Ferreira Center of Nuclear Technology Development. CDTN/CNEN.
  • Juliana Batista Silva Center of Nuclear Technology Development. CDTN/CNEN.
  • Marcelo Mamede Federal University of Minas Gerais. UFMG

DOI:

https://doi.org/10.15392/bjrs.v8i2.1196

Keywords:

positron emission tomography, quality control, NEMA NU 4-2008

Abstract

This work aims to evaluate the quality control program for small animal PET (positron emission tomography) scanners in Brazil. A questionnaire focused on type of small animal PET scanner and quality assurance program was prepared and sent to all Brazilian preclinical molecular imaging services that participated in the first Brazilian microPET/SPECT/CT users meeting held at the Federal University of Rio de Janeiro. The answers were compiled and descriptive statistic was applied. There are six preclinical molecular imaging services using PET scanner in Brazil. Five are in the southeastern region and one in the southern region. All services have a single PET device, but most of them have hybrids modalities with CT (computed tomography) and/or SPECT (single photon emission computed tomography). All services have knowledge of the NEMA NU 4-2008 publication specific to small animal PET equipments. However, most of them do not have a quality assurance program in place for their imaging systems. There are few preclinical PET devices installed in Brazil and most of them are located at southeastern region. Regardless the absence of quality assurance program in many of the services, there is a consensus on the importance of quality control program implementation.

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Author Biographies

Rodrigo Modesto Gadelha Gontijo, Federal University of Minas Gerais. UFMG

Department of Anatomy and Imaging (IMA)

Andréa Vidal Ferreira, Center of Nuclear Technology Development. CDTN/CNEN.

Radiopharmaceuticals Research and Production Unit (UPPR).

Juliana Batista Silva, Center of Nuclear Technology Development. CDTN/CNEN.

Radiopharmaceuticals Research and Production Unit (UPPR).

Marcelo Mamede, Federal University of Minas Gerais. UFMG

Department of Anatomy and Imaging (IMA).

References

YAO R.; LECOMTE R.; CRAWFORD E. Small-Animal PET: What is it, and why do we need it? Journal of Nuclear Medicine Technology. Vol. 40 nº3, pp.157-165. 2011.

NEMA - National Electrical Manufacturers Association. Performance Measurements of Small Animal Positron Emission Tomographs. Rosslyn VA; 2008 Standards Publication NU 4-2008.

CNEN - Comissão Nacional de Energia Nuclear. Requisitos de segurança e proteção radioló-gica para serviços de medicina nuclear, Norma CNEN NN 3.05. December, 2013.

IAEA - International Atomic Energy Agency (IAEA). Quality Control Guidance for Nuclear Medicine Equipment. Guidelines of Radiation and Nuclear Safety Authority – STUK, 2010.

GONTIJO, R. M. G. Proposta de Programa de Garantia da Qualidade para Imagem Mole-cular Pré-Clínica. 2019. 275 f. Tese (Doutorado em Ciência e Tecnologia das Radiações, Mi-nerais e Materiais) – Centro de Desenvolvimento da Tecnologia Nuclear, Comissão Nacional de Energia Nuclear, Belo Horizonte, 2019.

GONTIJO, R. M. G., FERREIRA, A. V., SILVA, J. B., MAMEDE, M. Image quality assess-ment using NEMA NU 4/2008 standards in small animal PET scanner. Brazilian Journal of Radiation Sciences. 07 (2A). pp. 1-13. 2019.

BEGERON, M., CADORETTE, J., TÉTRAULT, M. A., BEAUDOIN, J. F., LEROUX, J. D., FONTAINE, R. and LECOMTE, R., Imaging performance of LabPET APD-based digital PET Scanners for pre-clinical research. Physics in Medicine and Biology. v.59, pp. 661-678. 2014.

RATIB, O., ZAID, H., PRASAD, R. NEMA NU-04-based Performance Characteristics of the Lab-PET-8TM Small Animal PET Scanner. IEEE Nuclear Science Symposium Conference Record. pp. 3654-3659. 2011.

GAITANIS, A., KASTIS, G. A., VLASTOU. E., BOUZIOTIS, P., VERGINIS, P., ANAGNOSTO-POULOS, C. D., Investigation of Image Reconstruction Parameters of the Mediso nanoScan PC Small-Animal PET/CT Scanner for Two Different Positron Emitters Under NEMA NU 4-2008 Standards. Molecular Imaging and Biology. v.19, pp. 550–559. 2016.

DISSELHORST, J. A., BROM, M., LAVERMAN. P., SLUMP, C. H., BOERMAN, O. C., OYEN, W. J. G., GOTHARDT, M., VISSER E. P., Image-Quality Assessment for Several Positron Emitters Using the NEMA NU 4-2008 Standards in the Siemens Inveon Small-Animal PET Scan-ner. The Journal of Nuclear Medicine. v.51 (4), pp.610–617. 2010.

GOERTZEN A. L., NEMA NU 4-2008 Comparison of Preclinical PET Imaging Systems. The Journal of Nuclear Medicine. v.53 (8), pp.1300–1309. 2012.

ANVISA – Brazilian Healthy Regulatory Agency. RDC nº64. Radiopharmaceuticals reg-istration. 2009.

CNEN - Comissão Nacional de Energia Nuclear. Authorized installations. Available in: <http://www.cnen.gov.br/index.php/instalacoes-autorizadas-2>. September, 2019.

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Published

2020-06-30

How to Cite

Gadelha Gontijo, R. M., Ferreira, A. V., Silva, J. B., & Mamede, M. (2020). Quality control of small animal PET scanner: The Brazilian Scenario. Brazilian Journal of Radiation Sciences, 8(2). https://doi.org/10.15392/bjrs.v8i2.1196

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