Manufacture and characterization of a Bolus composed of water, bi-distilled glycerin, gelatin and formaldehyde

Authors

  • Carlla da Motta Oliveira Hospital Erasto Gaertner
  • Fábio Fernandes Brüning
  • Jessé Gevezier Prado Lyra
  • Susan Yamamoto Zanetti
  • Melissa Funchal
  • Tatiane Cristina de Oliveira Fernandes

DOI:

https://doi.org/10.15392/bjrs.v8i3.1206

Keywords:

medical physics, radiotherapy, bolus, material characterization.

Abstract

In years the bolus is used as human tissue compensator in treatments of superficial tumors using photons and electrons in the radiotherapy. In order to obtain a low cost and noncommercial bolus, it is proposed in this work to find an optimized bolus recipe composed of: water, bidistilled glycerin, gelatin and formol. It was manufactured 14 samples and it was evaluated their mass densities, homogeneity and malleability which M and N samples was classified for dosimetric analyses. The percentage depth dose (PDD) curves of M and N samples were measured and compared to the PTW RW3 solid water PDD curve for three energies, 6 MV, 6 MeV and 18 MeV. The PDDs comparisons results showed good agreement and differences smaller than 6% in the percentage depth values for depths smaller than 1,5 cm, except to 6 MeV electron energy which the sample N had difference of 17%. The M sample presented better results for the three measured energies and it was defined as the best recipe to a bolus between the analyzed samples in this work.

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Author Biography

Carlla da Motta Oliveira, Hospital Erasto Gaertner

Medical Physics of Erasto Gaertner Hospital

References

INCA – Instituto Nacional do Câncer. Tratamento do câncer: Radioterapia. Rio de Janeiro, Rio de Janeiro, Brazil. 2019. Available at: <https://www.inca.gov.br/tratamento/radioterapia>. Last accessed: 09 Dec. 2019.

KHAN, F.M.; GIBBISON, J.P.; SPERDUTO, P.W. Treatment planning in Radiation Oncology. 4th ed. Philadelphia: Wolters Kluwer, 2016.

RINGBORG, U; et al. The Swedish Council on Technology Assessment in Health Care (SBU) Systematic Overview of Radiotherapy for Cancer including a Prospective Survey of Radiotherapy Practice in Sweden 2001 - Summary and Conclusions The Swedish Council on Technology Assessment. Acta Oncologica, v. 42, p.357–365, 2003.

DOROTHY, A.; MATTHEW, K. L. The Evolution of Radiation Therapy in Treating Cancer. Seminars in Oncology Nursing, v. 34(2), p. 151-157, 2018.

Radiation Oncology. Targeting Cancer. Sydney. 2017. Available at: <https://www.targetingcancer.com.au/about-radiation-oncology/benefits-and-effectiveness/>. Last accessed: 10 Dec. 2019.

SCRIPES, P. G.; MORAES, S.; ROCHA; J. R. O. Verificação da Densidade Eletrônica e da Equivalência a Água dos Materiais Utilizados como Bólus (Cera e Gaze Vaselinada) em Radioterapia. 2006.

SPEZZIA, S. O uso do bolus na radioterapia. Revista da Faculdade de Ciências Médicas de Sorocaba, v. 18(4). p. 183-186, 2016.

WHITE, D. R. Tissue substitutes in experimental radiation physics. Medical physics, v. 5(6), p. 467-479, 1978.

WATSON, P.E.; WATSON, I.D; BATT, R.D. Total body water volumes for adult males and females estimated from simple anthropometric measurements. Am J Clin Nutr. v. 33(1), p. 27-39, 1980.

VYAS, V.; PALMER, L.; MUDGE, R.; JIANG, R.; FLECK, A.; SCHALY, B.; OSEI, E; CHARLAND, P. On bolus for megavoltage photon and electron radiation therapy. Medical Dosimetry, v. 38(3), p. 268-273, 2013.

ADAMSON, J. D.; COONEY, T.; DEMEHRI, F.; STALNECKER, A.; GEORGAS, D.; YIN, F. F.; KIRKPATRICK, J. Characterization of water-clear polymeric gels for use as radiotherapy bolus. Technology in cancer research & treatment. v. 16(6), p. 923-929, 2017.

FEEMAN, T. G. The Mathematics of Medical Imaging: A Beginner’s Guide. Springer Undergraduate Texts in Mathematics and Technology. 2010.

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Published

2020-09-27

How to Cite

Oliveira, C. da M., Brüning, F. F., Lyra, J. G. P., Zanetti, S. Y., Funchal, M., & Fernandes, T. C. de O. (2020). Manufacture and characterization of a Bolus composed of water, bi-distilled glycerin, gelatin and formaldehyde. Brazilian Journal of Radiation Sciences, 8(3). https://doi.org/10.15392/bjrs.v8i3.1206

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