Personal monitoring of cutaneous vitamin D3 production through a printable UV molecular dosimeter
DOI:
https://doi.org/10.15392/bjrs.v10i2A.2032Keywords:
printable dosimeter, UV molecular dosimetry, vitamin D3, personal dosimetryAbstract
Cutaneous production of vitamin D by exposure of the skin to solar radiation can provide more than 90% of the daily dose needed by the human body, thanks to the range of UV radiation covered by its spectrum and may be the best option to reduce oral supplementation. The process can be monitored by personal UV dosimetry since this is the range of solar radiation related to its production. Aiming to monitor UVB dose looking for correlation with skin production of vitamin D3, a printed strip with the molecular dosimetry device was used to produce a photonic signal as input for calculations in software developed here to run on a smartphone. For this, the molecular dosimeter Eu(btfa)3·bipy was prepared to be printed as a functional ink with a MEMS-based Drop-on-Demand Dimatix DMP2831 Materials Printer to produce the functional paper strips. To use our personal UV molecular dosimeter photonic signal as input data, a correlation curve must be established to convert the UV dose into the amount of vitamin D3 produced. There is a promising solution for personal monitoring of cutaneous vitamin D production by printable UV dosimeter targets, aiming to contribute to a better immune response of individuals. In addition, the creation of a cloud data lake capable of mapping population data on vitamin D deficiency can help define public health policies.
- Views: 321
- PDF Downloads: 229
Downloads
References
DROR A.A.; MOROZOV N.; DAOUD A.; NAMIR Y.; YAKIR O.; SHACHAR Y. et al. Pre-infection 25-hydroxyvitamin D3 levels and association with severity of COVID-19 illness. PLOS ONE, 17(2): e0263069, 2022. DOI: https://doi.org/10.1371/journal.pone.0263069
GAMEIRO, C. G.; SILVA JÚNIOR, E. F.; ACHETE, C. A.; SIMAO, R. A.; SANTA-CRUZ, P. A. UV personal Dosimeters of lanthanide complex films: a new molecular photonic device characterized by AFM. In: The 13th International Conference on Solid State Dosimetry, 2001, Atenas. Proc. SSD 2001. Ashford: Nuclear Technology publishing, 2001. v. 1. p. 37.
SOUSA, F.L.N.; MOJICA-SÁNCHEZ, L.C.; GAVAZZA, S.; FLORENCIO, L.; VAZ, E.C.R.; SANTA-CRUZ, P.A. Printable UV personal dosimeter: sensitivity as a function of DoD parameters and number of layers of a functional photonic ink. Mater. Res. Express, v. 3(4), 045701, 2016. DOI: https://doi.org/10.1088/2053-1591/3/4/045701
SANTA-CRUZ, P. A. Dosímetro Imprimível para Radiação Ultravioleta. Depositor: UFPE. PI10030263. Patent deposit: 06 Ago. 2010. Issued: 21 Sept. 2021.
VAZ, E.C.R.; DOMINGUES, T.A.L.; SANTOS, T.E.C; MOURA, L.A; TAVARES, T.; MELO, L.F.M.; MELO, S.B.; SANTA-CRUZ, P.A. Personal monitoring of cutaneous vitamin D3 production using smartphone through printable UV molecular dosimetry strips, In: 1st Latin American Congress on Solid State Dosimetry and Radiation Measurements, 2021, Recife. Annals... 2021, 245-1. Available at: https://grupodoin.com/evento_1/abstract.htm Last accessed: 02 Mar. 2022.
GAMEIRO, C. G.; da SILVA JR., E. F.; ALVES JR., S.; de SÁ G. F.; SANTA-CRUZ, P. A. Molecular dosimeter developed from high efficient rare-earth complexes: UV-A, UV-B and UV-C responses Materials Science Forum, v. 315-317, p. 249-256, 1999. DOI: https://doi.org/10.4028/www.scientific.net/MSF.315-317.249
BATISTA H. J.; de ANDRADE A. V. M.; Longo R. L.; SIMAS A. M.; de SÁ G. F.; THOMPSON L. C. Synthesis, crystal structure determination and theoretical prediction of the structure and electronic spectrum of Eu(btfa)3 bipy. J. Luminescence, v. 72-4, p.159, 1997. DOI: https://doi.org/10.1016/S0022-2313(96)00158-5
SERRANO, M.A. Contribution of sun exposure to the vitamin D dose received by various groups of the Spanish population. Sci. Total Environ., v. 619–620, p. 545-551, 2018. DOI: https://doi.org/10.1016/j.scitotenv.2017.11.036
BOGH, M.K.B.; SCHMEDES, A. V.; PHILIPSEN, P. A.; THIEDEN, E.; WULF, H. C. Vitamin D production depends on ultraviolet-B dose but not on dose rate: A randomized controlled trial. Exp. Dermatol. v. 20, p. 14-18, 2010. DOI: https://doi.org/10.1111/j.1600-0625.2010.01201.x
JAGER, N.; SCHÖPE, J.; WAGENPFEIL, S.; BOCIONEK, P.; SATERNUS, R.; VOGT, T.; REICHRATH, J. The impact of UV-dose, body surface area exposed and other factors on cutaneous vitamin D synthesis measured as serum 25(OH)D concentration: systematic review and meta-analysis. Anticancer Res., v. 38 (2), p.1165-1171, 2018. DOI: https://doi.org/10.21873/anticanres.12336
POPE, S.J.; HOLICK, M.F.; MACKIN, S.; GODAR, D.E. Action spectrum conversion factors that change erythemally weighted to previtamin D3-weighted UV doses. Photochem. Photobiol. 84, 1277–1283, 2008. DOI: https://doi.org/10.1111/j.1751-1097.2008.00373.x
Commission Internationale de L'Eclairage (CIE) and World Meteorological Organization (WMO), 2014. CIE 209:2014. WMO/GWA Report No. 211. Rationalizing Nomenclature for UV Doses and Effects on Humans. CIE, Vienna. Available at: https://library.wmo.int/pmb_ ged/gaw_211_en.pdf.. Last accessed: 15 Dec. 2021.
MCKENZIE, R.L.; LILEY, J.B.; BJÖRN, L.O. UV radiation: balancing risks and benefits. Photochem. Photobiol., v.85, p. 88–98, 2009. DOI: https://doi.org/10.1111/j.1751-1097.2008.00400.x
FITZPATRICK, T.B. The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol., v. 124, p. 869–871, 1988. DOI: https://doi.org/10.1001/archderm.124.6.869
GODAR, D.E.; POPE, S.J.; GRANT, W.B.; HOLICK, M.F. Solar UV doses of adult Americans and vitamin D3 production. Dermato-Endocrinol., v.3, p.243–250, 2011. DOI: https://doi.org/10.4161/derm.3.4.15292
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2022 Brazilian Journal of Radiation Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
Licensing: The BJRS articles are licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
