Dosimetric assessment and secondary cancer risk in breast radiotherapy: a Monte Carlo approach

Mirko Salomón Alva-Sánchez; Giulia Rita  de Souza Faés; William  de Souza Santos; Thatiane  Alves Pianoschi Alva

doi:10.15392/bjrs.v10i3.2064

Authors

Mirko Salomón Alva-Sánchez Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)/ Departamento de Ciências Exatas e Sociais Aplicados, 90050-170, Porto Alegre,Rio Grande do Sul, Brasil.
Giulia Rita de Souza Faés Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), 90050-170, Porto Alegre,Rio Grande do Sul, Brasil.
William de Souza Santos Universidade Federal de Uberlândia (UFU)/ Instituto de Física, 38.400-902, Uberlândia, Minas Gerais,Brasil
Thatiane Alves Pianoschi Alva Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)/ Departamento de Ciências Exatas e Sociais Aplicados, 90050-170, Porto Alegre,Rio Grande do Sul, Brasil.

DOI:

https://doi.org/10.15392/bjrs.v10i3.2064

Keywords:

Breast cancer, radiotherapy, dosimetry, anthropomorphic simulator, Monte Carlo

Abstract

To calculate the risk of secondary cancer induction resulting from this dose through a Monte Carlo simulation code and voxel-based anthropomorphic phantom to determine the radiation dose in organs and/or tissues with dosimetric importance and the effect of using static MLC in the 3D-CRT technique. In this work, a radiotherapy treatment of breast cancer was simulated using the radiation transport code MCNPX 2.7.0 and the adult anthropomorphic simulator FSTA_H50_M50. The absorbed doses for a set of organs with dosimetric importance were determined. A LINAC Varian 2100C device operated with two techniques was simulated: 2D with open field (OF) and 3D-conformational (3D-CRT), the latter with the use of a multilayer collimator (MLC) of the breast, both acting with 6 MV energy. The highest values of absorbed dose were obtained for the ipsilateral lung (7.22 Gy (3D-CRT) and 8.49 Gy (OF)) and the contralateral breast (6.29 Gy (3D-CRT) and 6.56 Gy (OF)), generating for these organs the greatest risks of secondary cancer induction. With the OF technique, due to the non-collimation of the beam, there was an increase in the absorbed dose in all organs compared to 3D-CRT, thus evidencing a more effective treatment with the 3D-CRT technique, improving both homogeneity and conformity with the dose absorbed in the target organ.

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Author Biography

Mirko Salomón Alva-Sánchez, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)/ Departamento de Ciências Exatas e Sociais Aplicados, 90050-170, Porto Alegre,Rio Grande do Sul, Brasil.

Department of Exact Science and Applied Social

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