Desenvolvimento de técnicas de bioanálise in vitro para monitoração individual de 32P

Authors

  • Ana Letícia Almeida Dantas Instituto de Radioproteção e Dosimetria - IRD-CNEN
  • Ana Paula Fonseca de Almeida IRD - CNEN
  • Wanderson Oliveira Sousa IRD-CNEN
  • Bernardo Maranhão Dantas IRD-CNEN

DOI:

https://doi.org/10.15392/bjrs.v5i3-A.293

Keywords:

phosphorus-32, Colorimetric Quenching, Cerenkov Effect

Abstract

The 32P is used in the form of liquid unsealed sources in medical facilities, research and teaching, representing a risk of internal exposure in routine activities and in case of accidental incorporation. The evaluation of 32P incorporation can be accomplished through in vitro bioanalysis of urine. This paper aims to provide a methodology to analyze 32P in biological samples, applicable to internal individual monitoring using liquid scintillation technique. The minimum detectable activity of the system was determined and the sensitivity of the technique was evaluated, based on the detected minimum effective dose.

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References

IAEA - International Atomic Energy Agency. Assessment of Occupational Exposure Due to Intakes of Radionuclides Safety Standards Series RS-G-1.2, 1999

CNEN - Comissão Nacional de Energia Nuclear. Diretrizes Básicas de Proteção Radiológica. Norma CNEN-NN-3.01, 2014

IAEA - International Atomic Energy Agency. Methods for Assessing Occupational Radiation Doses due to Intakes of Radionuclides. Safety Reports Series 37, 2004

VIM - Vocabulário Internacional de Metrologia, Instituto Português de Qualidade. 1ª Ed. Luso- Brasileira, 2012

ICRP - International Commission on Radiological Protection. Individual Monitoring for Internal Exposure of Workers. Publication 78, 1998

BERTELLI, L.; MELO, D.R.; LIPSZTEIN, J.; CRUZ-SUAREZ, R. AIDE: Internal Dosimetry Software” Radiation Protection Dosimetry v. 130 (3), p. 35, 2008

Published

2017-11-20

Issue

Section

III Brazilian Congress on Metrology of Ionizing Radiation

How to Cite

Desenvolvimento de técnicas de bioanálise in vitro para monitoração individual de 32P. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 5, n. 3-A, 2017. DOI: 10.15392/bjrs.v5i3-A.293. Disponível em: https://bjrs.org.br/revista/index.php/REVISTA/article/view/293.. Acesso em: 22 nov. 2024.

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