Material imaging study of 3D printing materials for diagnostic radiology phantom development

Marcus Oliveira; Matheus Savi; Adriano  Vitor; Daniel  Villani; Marco Andrade; Carlos  Ubeda; Mauricio  Mitsuo Monção

doi:10.15392/2319-0612.2024.2556

Autores

Marcus Oliveira Federeal Institute of Education, Science, Technology of Bahia
Matheus Savi Department of Health. Federal Institute of Education, Science and Technology of Santa Catarina –IFSC
Adriano Vitor Department of Health. Federal Institute of Education, Science and Technology of Santa Catarina –IFSC
Daniel Villani Instituto de Pesquisas Energéticas e Nucleares – IPEN/USP
Marco Andrade Department of Health. Federal Institute of Education, Science and Technology of Santa Catarina –IFSC
Carlos Ubeda Medical Technology Department. Health Sciences Faculty, Tarapaca University, 1010069, Arica, Chile
Mauricio Mitsuo Monção Federeal Institute of Education, Science, Technology of Bahia, 40301-015, Salvador, Bahia, Brasil

DOI:

https://doi.org/10.15392/2319-0612.2024.2556

Palavras-chave:

Impressão 3D, fantoma, radiologia diagnóstica

Resumo

As técnicas de impressão 3D têm encontrado aplicações em diversos campos, melhorando significativamente os processos de design e fabricação. O impacto deste crescimento é perceptível na radiologia, onde a impressão 3D tem sido aplicada ao desenvolvimento de ferramentas de controle de qualidade e ao avanço de técnicas de dosimetria. A impressão 3D tem a vantagem de possuir uma grande variedade de materiais plásticos que podem ser utilizados no processo de fabricação. Há escassez de trabalhos desenvolvidos para avaliar a atenuação do feixe de raios X dos materiais utilizados na impressão de modelos 3D para desenvlvimento de fantomas. Este artigo tem como objetivo mostrar nossos resultados na pesquisa das características de imagem de 15 materiais impressos em 3D. Os objetos 3D foram impressos como cubos de 20 x 20 x 20 mm³ com preenchimento de 100%, padrão estrutural retilíneo de 45°/45°. As imagens foram adquiridas em uma unidade de raios X DR e foram analisadas com o software ImageJ. Os valores dos pixels de imagem, a relação sinal-ruído – SNR e a relação contraste-ruído – CNR foram avaliados e comparados entre os cubos impressos em 3D e um simulador de tórax padrão. Ao comparar a relação sinal-ruído para materiais plásticos e estruturas torácicas, foram encontradas diferenças significativas. Resultados semelhantes foram encontrados para o relação contraste-ruído. As diferenças foram notadas por meio do teste de Kruskal Wallis para os materiais plásticos Tungstênio e Bismuto que demonstraram valores estatisticamente significativos de relação sinal-ruído signal-to-noise ratio em comparação ao pulmão (p < 0,0001) e à costela direita (p < 0,0001). descobriu-se que os filamentos de tungstênio e bismuto têm potencial para representar o relação sinal-ruído para estruturas intermediárias e de alta densidade. a escápula foi a única estrutura anatômica sem diferença estatisticamente significativa do relação contraste-ruído em realação ao SILK (p ≥ 0,074), ABS (p ≥ 0,086), PVA (p ≥ 0,917) e ABSpremium (p ≥ 0,955). O estudo demonstrou potenciais materiais de impressão 3D para desenvolvimento de simuladores de radiologia diagnóstica e revelou importantes características de imagem para os materiais plásticos usando a técnica Fused Filament Fabrication.

Downloads

Os dados de download ainda não estão disponíveis.

Referências

CRAMER, J.; QUIGLEY, E.; HUTCHINS, T.; , SHAH, L. Educational Material for 3D Visualization of Spine Procedures: Methods for Creation and Dissemination J. Digit. Imaging, v.30, n.3,p.296-300, 2017. DOI: https://doi.org/10.1007/s10278-017-9950-0

KAMOMAE. T.;, SHIMIZU, H.; NAKAYA, T.; OKUDAIRA,K.;AOYAMA, T.; OGUCHI, H.; KOMORI, M.; KAWAMURA, M.; OHTAKARA,K.; MONZEN, H.; ITOH, Y.; NAGANAWA,S.; Three-dimensional printer-generated patient-specific phantom for artificial in vivo dosimetry in radiotherapy quality assurance Phys. Medica, v. 44 , p. 205-211, 2017 DOI: https://doi.org/10.1016/j.ejmp.2017.10.005

SCULPTEO. The State of 3D Printing Report 2018 Disponível em: https://www.sculpteo.com/en/ebooks/state-of-3d-printing-report-2018/. Acesso em: 27 ago. 2024

SHIN, J.; SANDHU, R.. S.; SHIH, G.; Imaging Properties of 3D Printed Materials: Multi-Energy CT of Filament Polymers J. Digit. Imaging, v.30,n.5, p.572–5, 2017 DOI: https://doi.org/10.1007/s10278-017-9954-9

YANG, L.; GROTTKAU, B.; HE, Z.; YE, C. Three dimensional printing technology and materials for treatment of elbow fractures Int. Orthop., v.41,p. 2381–2387, 2017. DOI: https://doi.org/10.1007/s00264-017-3627-7

FAROOQI, K. M.; SAEED, O.; ZAIDI, A.; SANZ, J.; NIELSEN, J. C.; HSU, D. T.; JORDE, U. P. 3D Printing to Guide Ventricular Assist Device Placement in Adults With Congenital Heart Disease and Heart Failure. JACC Hear. v.4,n.4, p.301-11, 2016 DOI: https://doi.org/10.1016/j.jchf.2016.01.012

SAVI, M.; ANDRADE, M. A. B.; POTIENS, M. P. A. Commercial filament testing for use in 3D printed phantoms, Radiat. Phys. Chem., v. 174, p, 108906, 2020 DOI: https://doi.org/10.1016/j.radphyschem.2020.108906

SAVI, M.; ANDRADE, M. A. B.; VILLANI, D., JUNIOR, O. R.; POTIENS, M. D.A. P. A. Development of radiopaque FFF filaments for bone and teeth representation in 3D printed radiological objects, Brazilian J. Radiat. Sci. v.10,n.1,p.01-22,2022. DOI: https://doi.org/10.15392/bjrs.v10i1.1739

KAPETANAKIS, I.; FOUNTOS, G.; MICHAIL, C.; VALAIS, I.; KALYVAS, N.; 3D printing X-Ray Quality Control Phantoms. A Low Contrast Paradigm, Journal of Physics: Conference Series,v.931,p. 012026,2017 DOI: https://doi.org/10.1088/1742-6596/931/1/012026

OLIVEIRA, M.; BARROS, J.C.; UBEDA, C. Development of a 3D printed quality control tool for evaluation of x-ray beam alignment and collimation, Phys. Medica, v. 65, p.29-32, 2019. DOI: https://doi.org/10.1016/j.ejmp.2019.07.026

PAXTON. N.; SMOLAN, W.; BÖCK, T.; MELCHELS, F.; GROLL, J.; JUNGST, T.; Proposal to assess printability of bioinks for extrusion-based bioprinting and evaluation of rheological properties governing bioprintability Biofabrication v.9,n.4,p.044107, 2017 DOI: https://doi.org/10.1088/1758-5090/aa8dd8

OGDEN,K. M.; MORABITO, K. E.; DEPEW, P. K.; 3D printed testing aids for radiographic quality control J. Appl. Clin. Med. Phys. v.20,n.5,p. 127–34,2019 DOI: https://doi.org/10.1002/acm2.12574

NOONOO. J, B.; SOSU, E.; HASFORD, F.; Three-dimensional image quality test phantom for planar X-ray imaging. S. Afr. J. Sci.v.119,n.7/8, p.1-7,2023 DOI: https://doi.org/10.17159/sajs.2023/14269

MADAMESILA, J.; MCGEACHY, P.; VILLARREAL, B.J. E.; KHAN, R. Characterizing 3D printing in the fabrication of variable density phantoms for quality assurance of radiotherapy, Phys. Medica, v.32,n1,p.242-247, 2016 DOI: https://doi.org/10.1016/j.ejmp.2015.09.013

GROENEWALD, A.; GROENEWALD, W. A. Development of a universal medical X-ray imaging phantom prototype J. Appl. Clin. Med. Phys. v.17,n.6,p356-365,2016. DOI: https://doi.org/10.1120/jacmp.v17i6.6356

SCHOPPHOVEN, S.; CAVAEL, P.; BOCK, K.; FIEBICH, M.; MÄDER, U. Breast phantoms for 2D digital mammography with realistic anatomical structures and attenuation characteristics based on clinical images using 3D printing Phys. Med. Biol.v. 64,n.21,p.215005,2019 DOI: https://doi.org/10.1088/1361-6560/ab3f6a

HE, Y.; LIU, Y.; DYER, B. A.; BOONE, J. M.; LIU, S.; CHEN, T.; ZHENG, F.; ZHU, Y.; SUN, Y.; RONG, Y.; QIU, J.;3D-printed breast phantom for multi-purpose and multi-modality imaging Quant. Imaging Med. Surg. v.9,n.1,p.63-74 ,634–74,2019. DOI: https://doi.org/10.21037/qims.2019.01.05

OLIVEIRA, M.; SAVI, M.; ANDRADE, M.; VILLANI, D.; POTIENS, M. P. A.; STUANI, H; UBEDA, C.; MDLETSHE, S.; Attenuation properties of common 3D printed FFF plastics for mammographic applications Brazilian J. Radiat. Sci.,v. 10.n.1,p.01-17,2022 DOI: https://doi.org/10.15392/bjrs.v10i1.1732

LEE, M. Y.; HAN, B.; JENKINS, C.; XING, L.; SUH, T. S.; A depth-sensing technique on 3D-printed compensator for total body irradiation patient measurement and treatment planning Med. Phys. v.43,n.11,p.6137,2016 DOI: https://doi.org/10.1118/1.4964452

JAVAN, R.; BANSAL, M.; TANGESTANIPOOR, A. A prototype hybrid gypsum-based 3-dimensional printed training model for computed tomography-guided spinal pain management J. Comput. Assist. Tomogr.v.40,n.4,p.626-631,2016 DOI: https://doi.org/10.1097/RCT.0000000000000415

KIM, M. J.; LEE, S. R.; LEE, M. Y.; SOHN, J. W.; YUN, H. G.; CHOI, J. Y.; JEON, S. W.; SUH, T. S. Characterization of 3D printing techniques: Toward patient specific quality assurance spine-shaped phantom for stereotactic body radiation therapy PLoS One, v.12,n.5,p.e0176227,2017 DOI: https://doi.org/10.1371/journal.pone.0176227

SILBERSTEIN, J. ; SUN, Z. Advances and Applications of Three-Dimensional-Printed Patient-Specific Chest Phantoms in Radiology: A Systematic Review Appl. Sci. v.. 14, p. 5467 14 5467, 2024 DOI: https://doi.org/10.3390/app14135467

Rasband W. ImageJ. Bethesda, Maryland, USA: U.S. National Institutes of Health; 1997e2012. Disponivél em:: http://imagej.nih.gov/ij/.

HUDA, W.; ABRAHAMS, R. B. Radiographic techniques, contrast, and noise in x-ray imaging. Am. J. Roentgenol. v.204,n.2,p. W126–31,2015 DOI: https://doi.org/10.2214/AJR.14.13116

BRODER, J. Imaging the Chest: The Chest Radiograph. In Diagnostic Imaging for the Emergency Physician, Expert Consult - Online and Print, p.185–296, 2011. DOI: https://doi.org/10.1016/B978-1-4160-6113-7.10005-5

DUKOV, N.; BLIZNAKOVA, K.; OKKALIDIS, N.; TENEVA, T.; ENCHEVA, E.; BLIZNAKOV, Z.; Thermoplastic 3D printing technology using a single filament for producing realistic patient-derived breast models, Phys. Med. Biol. v.67,n.4,p.045008,2022 DOI: https://doi.org/10.1088/1361-6560/ac4c30

GEAR, J. I.; LONG, C.; RUSHFORTH, D.; CHITTENDEN, S. J.; CUMMINGS, C.; FLUX, G. D. Development of patient-specific molecular imaging phantoms using a 3D printer Med. Phys. v. 41,n.8,p.082502,2014. DOI: https://doi.org/10.1118/1.4887854

ZHANG, F.; ZHANG, H.; ZHAO, H.; HE, Z.; SHI, .; HE, Y.; JU, N.;RONG, Y.; QIU, J. Design and fabrication of a personalized anthropomorphic phantom using 3D printing and tissue equivalent materials, Quant. Imaging Med. Surg. v.9,n.1,p.94-100,2019 DOI: https://doi.org/10.21037/qims.2018.08.01

ANWARI, V.; LAI, A.; URSANI, A.; REGO, K.; KARASFI, B.; SAJJA, S.; PAUL, N. 3D printed CT-based abdominal structure mannequin for enabling research. 3D Print. Med.v.6,n.1,p.1-12 ,2020 DOI: https://doi.org/10.1186/s41205-020-0056-9

PULLEN, M. W.; POOLEY, R. A.; KOFLER, J. M.;VALERO-MORENO, F.; RAMOS-FRESNEDO, A.; DOMINGO, R. A.; PEREZ-VEGA, C.; FOX, W. C.; SANDHU, S. J. S. QUINONES-HINOJOSA, A.; BUCHANAN, I. A. A radiographic analysis of common 3D print materials and assessment of their fidelity within vertebral models Ann. 3D Print. Med.v.8,p.1-7,2022 DOI: https://doi.org/10.1016/j.stlm.2022.100080

HUDA, W.; BRAD, A.R. X-ray-based medical imaging and resolution Am. J. Roentgenol. v.204,n.4,p. W393–397,2015 DOI: https://doi.org/10.2214/AJR.14.13126

ZHAO, Y.; MORAN, K.; YEWONDWOSSEN, M.; ALLAN, J. CLARKE, S.; RAJARAMAN, M.; WILKE, D.; JOSEPH, P.; ROBAR, J. L. Clinical applications of 3-dimensional printing in radiation therapy Med. Dosim. v.42,n.2,p. 150–155,2017 DOI: https://doi.org/10.1016/j.meddos.2017.03.001

CEH, J.; YOUD, T.; MASTROVICH, Z.; PETERSON, C.; KHAN, S.; SASSER, T. A.; SANDER, I. M.; DONEY, J.; TURNER, C.; LEEVY, W. M. Bismuth Infusion of ABS Enables Additive Manufacturing of Complex Radiological Phantoms and Shielding Equipment. Sensors (Basel).v. 17,n.3,p.459,2017 DOI: https://doi.org/10.3390/s17030459

JUNG, J.; SONG, S. Y.; YOON, S. M.; KWAK, J.; YOON, K.; CHOI, W.; JEONG, S. Y.; CHOI, E. K.; CHO, B. Verification of accuracy of CyberKnife tumor-tracking radiation therapy using patient-specific lung phantoms Int. J. Radiat. Oncol. Biol. Phys.v. 92,n.4,p.745-753,2015 DOI: https://doi.org/10.1016/j.ijrobp.2015.02.055

PALLOTTA, S.; CALUSI, S.; FOGGI, L.; LISCI, R.; MASI, L.; MARRAZZO, L. TALAMONTI, C.; LIVI, L.; SIMONTACCHI, G.ADAM: A breathing phantom for lung SBRT quality assurance Phys. Medica,v.49,p.147-155,2018 DOI: https://doi.org/10.1016/j.ejmp.2017.07.004

LARSSON, J.; LIAO, P.; LUNDIN, P.; KRITE, S.E., SWARTLING, J.; LEWANDER, X. M.; BOOD, J.; ANDERSSON-ENGELS, S. Development of a 3-dimensional tissue lung phantom of a preterm infant for optical measurements of oxygen—Laser-detector position considerations, J. Biophotonics,v.11,n.3,p.1-8,2017 DOI: https://doi.org/10.1002/jbio.201700097

HAZELAAR, C.; VAN EIJNATTEN. M.; DAHELE, M.; WOLFF, J.; FOROUZANFAR, T.; SLOTMAN, B.; VERBAKEL, W. F. A. R. Using 3D printing techniques to create an anthropomorphic thorax phantom for medical imaging purposes Med. Phys. v.45,n.1,p.92-100,2018. DOI: https://doi.org/10.1002/mp.12644

KAIRN, T.; CROWE, S. B.; MARKWELL, T. Use of 3D printed materials as tissue-equivalent phantoms In: Jaffray, D. (eds) World Congress on Medical Physics and Biomedical Engineering, Toronto, Canada. IFMBE Proceedings,v.51,p.728-729,2015 DOI: https://doi.org/10.1007/978-3-319-19387-8_179