A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

Fabiana Trevisan; Beatriz Nascimento; Gabriel Chibana; Luciana Maeda; Marta Vila; Valquiria Yoshida; Norberto Aranha; Victor M. Balcão; José Martins Oliveira Júnior

doi:10.15392/2319-0612.2023.2158

Authors

Fabiana Trevisan University of Sorocaba https://orcid.org/0000-0002-5542-7744
Beatriz Nascimento IDS - Institute of Diagnosis of Sorocaba https://orcid.org/0000-0002-4456-7557
Gabriel Chibana Hospital Santa Marcelina https://orcid.org/0009-0006-5616-2000
Luciana Maeda Hospital Santa Marcelina https://orcid.org/0000-0003-2615-0501
Marta Vila University of Sorocaba https://orcid.org/0000-0002-0198-7076
Valquiria Yoshida University of Sorocaba https://orcid.org/0000-0003-2022-4485
Norberto Aranha University of Sorocaba https://orcid.org/0000-0003-1954-377X
Victor M. Balcão University of SorocabaPhageLab - Laboratory of Biofilms and BacteriophagesCidade Universitária Prof. Aldo VannucchiRodovia Raposo Tavares, km 92.5CEP 18023-000 Sorocaba/SPBrazil https://orcid.org/0000-0003-0772-2834
José Martins Oliveira Júnior University of Sorocaba https://orcid.org/0000-0001-6435-1908

DOI:

https://doi.org/10.15392/2319-0612.2023.2158

Keywords:

Radionuclide Imaging, Pediatric Nephrology, Renal cortical scintigraphy

Abstract

Purpose. This work aimed at evaluating the possibility of performing renal exams of dynamic renal (DRS) and static renal (SRS) scintigraphy on the same day (one-day protocol, ODP), exams that are currently performed in two days. Approach. 25 infants (50 kidneys) of both genders, aged 8.4 ± 5.9 years, underwent an F+20 DRS protocol with [^99mTc]TcDTPA^2- followed by [^99mTc]TcDMSA^2- administration for the performance of SRS images at 3, 6 and 24 h. Dynamic images (DRS) were classified as dilated (D), undetermined (U), and non-dilated (P). Static images (SRS) were classified as: depressed in accented degree (DA); depressed in moderate degree (DM); depressed in mild degree (DL) and normal (NL). Results. Out of the 25 patients (50 kidneys), 7 (14 kidneys) were excluded by functional exclusion, hence 18 patients (36 kidneys) were clinically compared regarding their static images after 3, 6 and 24 h, resulting in 33.0% of dilated and 66.7% non-dilated. Only two patients of the dilated group were classified as obstructed. At the group with non-dilated and dilated but non-obstructed kidneys, 100% of them had the same clinical classification at 6 and 24 h images. Conclusions. Performance of both DRS and SRS exams in a single day for pediatric patients, when medical requests are carried out jointly, is feasible in a population with or without dilatation, when the difference between dynamic and static images is of at least 6 h. Due to the small number of obstructed kidneys in this study, further evaluation in this population is needed.

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Author Biography

Victor M. Balcão, University of SorocabaPhageLab - Laboratory of Biofilms and BacteriophagesCidade Universitária Prof. Aldo VannucchiRodovia Raposo Tavares, km 92.5CEP 18023-000 Sorocaba/SPBrazil

PhageLab - Laboratory of Biofilms and Bacteriophages

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