X- ray experimental set-up for in-vitro nail test

Cibele Bugno Zamboni; Dalton Nogueira da Silva Giovanni; Mateus Ramos de Almeida; Alberto Sabino Todo; Fabio Sabará Dias; Orlando Rodrigues Junior

doi:10.15392/2319-0612.2023.2207

Authors

Cibele Bugno Zamboni Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP
Dalton Nogueira da Silva Giovanni Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP https://orcid.org/0000-0001-7607-1612
Mateus Ramos de Almeida Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP https://orcid.org/0000-0002-3478-374X
Alberto Sabino Todo Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP
Fabio Sabará Dias Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP
Orlando Rodrigues Junior Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP

DOI:

https://doi.org/10.15392/2319-0612.2023.2207

Keywords:

nail, FRX, Ions

Abstract

In this investigation, the elements Ca and S were evaluated in a single nail clipping using compact and portable X-ray spectrometer model X-123 SDD with Ag target. Experimental conditions for current, voltage and excitation time were investigated. These analyses can be useful for a variety of applications, including nutritional and medical diagnosis, such as, the evaluation of bone dysfunctions by measurement of Ca (bone decalcification) and S for nutrition evaluations (collagen production). This analysis offers some benefits comparatively to blood and serum analyses, such as, non-invasive collection, fast analyses (minutes) and low cost. In addition, nail clippings are simple to obtain, easy to store, and easy to transport. This pilot study show a positive expectation for clinical application using in-vitro nail test.

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