Influence of the resolution mode on mean and maximum SUV for PET images acquired by a LabPET SOLO 4 scanner
DOI:
https://doi.org/10.15392/2319-0612.2023.2273Keywords:
LabPET SOLO 4, Resolution Mode, Standardized Uptake ValueAbstract
In preclinical PET, SUV (standardized uptake value) is a robust quantifier that can be used to analyze PET images. Several factors – biological or technical – can affect SUV determination. Among technical factors, it is possible to cite the reconstruction protocols of PET images. This work evaluated the influence of two resolution modes – standard and high – on mean and maximum SUVs. The PET image of a mouse with a tumor in left flank was chosen from a PET image bank and reconstructed using two different protocols varying the resolution mode. The post-processing of images was performed using AMIDE software and eight volumes of interest (VOIs) were defined. Qualitatively, there was light improvement in structures definition in high-resolution image compared to standard resolution image. At the semiquantitative analysis, image reconstruction protocols using high-resolution mode did not significantly improve the recuperation of radiopharmaceutical uptake into analyzed tissues.
- Views: 175
- PDF Downloads: 129
- XML Downloads: 10
Downloads
References
TAN, L. T.; Ong, K. L. Semi-quantitative Measurements of Normal Organs with Variable Metabolic Activity on FDG PET imaging. Ann Acad Med Singapore, v. 33, p. 183–185, 2011.
GONTIJO, R. M. G.; FERREIRA, A. V.; SOUZA, G. C. A.; MENDES, B. M.; SILVA, J. B.; MAMEDE, M. Image quality evaluation of a small animal PET scanner. Brazilian Journal of Radiation Sciences, v. 08-02, p. 01–13, 2020.
BARBOSA J. V. C.; GONTIJO, R. M. G.; SOUZA, G. C. A.; MENDES, B. M.; SILVA, J. B.; MAMEDEB, M.; FERREIRA, A.V. Influence of image reconstruction protocols on the image quality of a small animal PET scanner using 18F and 11C. Brazilian Journal of Radiation Sciences, v. 09-03, p. 01–19, 2019.
NEMA-National ElectricalManufacturers Association. Performance Measurements of Small Animal PET, Rosslyn VA; Standards Publication NU 4-2008, 2008.
OIKONEN, V. Standardized uptake value (SUV), Turku Pet Centre. Turku, Finland. 2020. Available at: <http://www.turkupetcentre.net/petanalysis/model_suv.html>. Last accessed: 18 Jan. 2022.
ADAMS, M. C.; TURKINGTON, T. G.; WILSON, J. M.; WONG, T. Z. A Systematic Review of the Factors Affecting Accuracy of SUV Measurements. American Journal of Roentgenology, v. 195, n. 2, p. 310–320, 2010.
BRENDLE, C.; KUPFERSCHLÄGER, J.; NIKOLAOUA, K.; FOUGÈRE, C.; GATIDIS, S.; PFANNENBERGA, C. Is the standard uptake value (SUV) appropriate for quantification in clinical PET imaging? – Variability induced by different SUV measurements and varying reconstruction methods. European Journal of Radiology. v. 84, n. 1, p. 158-162, 2015.
SAHA, G. B. Basics of PET Imaging: Physics, Chemistry, and Regulations, 2th ed., Springer New York, NY, 2010. p. 83-84.
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Brazilian Journal of Radiation Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
Licensing: The BJRS articles are licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/