Influence of the resolution mode on mean and maximum SUV for PET images acquired by a LabPET SOLO 4 scanner

Authors

  • João Vitor do Carmo Barbosa Centro de Desenvolvimento da Tecnologia Nuclear
  • Guilherme Cavalcante Albuquerque de Souza Centro de Desenvolvimento da Tecnologia Nuclear
  • Rodrigo Modesto Gadelha Gontijo Universidade Federal de Minas Gerais
  • Bruno Melo Mendes Centro de Desenvolvimento da Tecnologia Nuclear
  • Andrea Vidal Ferreira Centro de Desenvolvimento da Tecnologia Nuclear

DOI:

https://doi.org/10.15392/2319-0612.2023.2273

Keywords:

LabPET SOLO 4, Resolution Mode, Standardized Uptake Value

Abstract

In preclinical PET, SUV (standardized uptake value) is a robust quantifier that can be used to analyze PET images. Several factors – biological or technical – can affect SUV determination. Among technical factors, it is possible to cite the reconstruction protocols of PET images. This work evaluated the influence of two resolution modes – standard and high – on mean and maximum SUVs. The PET image of a mouse with a tumor in left flank was chosen from a PET image bank and reconstructed using two different protocols varying the resolution mode. The post-processing of images was performed using AMIDE software and eight volumes of interest (VOIs) were defined. Qualitatively, there was light improvement in structures definition in high-resolution image compared to standard resolution image. At the semiquantitative analysis, image reconstruction protocols using high-resolution mode did not significantly improve the recuperation of radiopharmaceutical uptake into analyzed tissues.

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References

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Published

2023-08-24

How to Cite

Barbosa, J. V. do C., Souza, G. C. A. de, Gontijo, R. M. G., Mendes, B. M., & Ferreira, A. V. (2023). Influence of the resolution mode on mean and maximum SUV for PET images acquired by a LabPET SOLO 4 scanner. Brazilian Journal of Radiation Sciences, 11(3), 1–11. https://doi.org/10.15392/2319-0612.2023.2273

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