A Comparison of Planned Dose in TBI VMAT Treatment with Dosimetry Using Portal Dosimetry® and IBA MatriXX®

Juan Sousa; I Lima; D Olbi; Lucas Nascimento; Andre Fidelis; Maria Luiza Maciel; Luiz da Rosa; Simone Coutinho Cardoso

doi:10.15392/2319-0612.2024.2683

Authors

Juan Sousa Grupo Oncoclínicas, Rio de Janeiro, Brasil
I Lima Programa de Pós-graduação em Engenharia Nuclear, COPPE, UFRJ, Rio de Janeiro Brasil
D. Olbi Grupo Oncoclínicas, Rio de Janeiro, Brasil.
Lucas Nascimento Instituto de Física, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brasil
Andre Fidelis Programa de Pós-graduação em Radioproteção e Dosimetria (IRD/CNEN), Rio de Janeiro, Brasil.
Maria Luiza Maciel Instituto de Física, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brasil
Luiz Antonio Ribeiro da Rosa Programa de Pós-graduação em Radioproteção e Dosimetria (IRD/CNEN), Rio de Janeiro, Brasil.
Simone Coutinho Cardoso Instituto de Física, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brasil

DOI:

https://doi.org/10.15392/2319-0612.2024.2683

Keywords:

Portal Dosimetry, IBA MatriXX, BMT, TBI, VMAT

Abstract

Bone Marrow Transplant (BMT) is an essential therapeutic intervention in the treatment of diseases such as leukemia and lymphoma, where Total Body Irradiation (TBI) plays a crucial role by eradicating residual diseases and inducing immunosuppression, thus facilitating cell transplantation and reducing the risk of graft rejection. Traditionally, TBI has used large radiation fields, which can lead to significant toxicities in organs at risk (OARs) due to challenges in dose optimization. Volumetric Modulated Arc Therapy (VMAT) emerges as a promising technique, offering advantages such as the use of smaller treatment spaces and reduced doses to OARs, which may improve patient quality of life and reduce treatment costs. This study evaluates the effectiveness of VMAT in TBI by comparing the planned dose with the dose measured by quality control systems, such as the MatriXX FFF from IBA and the Portal Dosimetry from the VitalBeam linear accelerator, demonstrating that VMAT is a viable and effective alternative with the potential to optimize therapeutic outcomes in BMT.

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References

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