Medical imaging technologies applied to the COVID-19 context

Authors

DOI:

https://doi.org/10.15392/2319-0612.2022.2060

Keywords:

COVID-19, diagnostic imaging, radiology

Abstract

Since the outbreak of COVID-19 disease, imaging methods such as X-Ray and Computed Tomography have stood out as feasible tools for diagnosing and evaluating the disease, especially regarding its lung occurrence in symptomatic patients. However, in the course of the pandemic, COVID-19 showed its effects in other tissues such as heart, brain and veins, triggering inflammatory processes. Thus, other imaging methods such as Positron Emission Tomography-Computer Tomography (PET-CT) and Magnetic Resonance have shown to be good sources of information about the location and intensity of the inflammation. This article reviews some of these imaging methods, its findings, feasibilities, advantages and limitations for COVID-19 diagnostic and evaluating.

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Author Biographies

  • Rodrigo Modesto Gadelha Gontijo, Universidade Federal de Minas Gerais

    Departamento de Anatomia e Imagem/Faculdade de Medicina

  • Andréa Vidal Ferreira, Centro de Desenvolvimento de Tecnologia Nuclear (CDTN/CNEN)

    SERFA/CDTN/CNEN

References

TORRES, P.P.T.S.; IRIONA, K.L.; MARCHIORIA, E. COVID-19: chest X-rays to predict clinical outcomes. J Bras Pneumol, v. 46, e20200464, p. 1-2, 2020. DOI: https://doi.org/10.36416/1806-3756/e20200464

WONG, H.Y.F.; LAM, H.Y.S.; FONG, A.H.; LEUNG, S.T.; CHIN, T.W.; LO, C.S.Y;. LUI, M.M.; LEE, J.C.Y.; CHIU, K.W.; CHUNG, T.W.; LEE, E.Y.P.; WAN, E.Y.F.; HUNG, I.F.N.; LAM, T.P.W.; KUO, M.D.; NG, M.Y. Frequency and Distribution of Chest Radiographic Findings in Patients Positive for COVID-19. Radiology, v.296, p. 72-78, 2020. DOI: https://doi.org/10.1148/radiol.2020201160

MARTÍNEZ, C.E.; DÍEZ, T.A.; IBÁÑEZ, S.L.; OSSABA, V.S.; BORRUEL, N.S. Radiologic diagnosis of patients with COVID-19. Radiologia (Engl Ed). v.63, p. 56-73, 2021. DOI: https://doi.org/10.1016/j.rxeng.2020.11.001

ACR - American College of Radiology. Recommendations for the use of Chest Radiography and Computed Tomography (CT) for Suspected COVID-19 Infection. March 22, 2020.

MANNA, S.; WRUBLE, J.; MARON, S.Z.; TOUSSIE, D.; VOUTSINAS, N.; FINKELSTEIN, M.; CEDILLO, M.A.; DIAMOND, J.; EBER, C.; JACOBI, A.; CHUNG, M.; BERNHEIM, A. COVID-19: A Multimodality Review of Radiologic Techniques, Clinical Utility, and Imaging Features. Radiol Cardiothoracic Imaging, v. 2, e200210, 2020 DOI: https://doi.org/10.1148/ryct.2020200210

NAVA-MUÑOZ, Á.; GÓMEZ-PEÑA, S.; FUENTES-FERRER, M.E; CABEZA, B.; VICTORIA, A.; BUSTOS, A. COVID-19 pneumonia: Relationship between initial chest X-rays and laboratory findings. Radiologia (Engl Ed), v. 63, p. 484-494, 2021 DOI: https://doi.org/10.1016/j.rxeng.2021.06.003

FANG, Y.; ZHANG, H.; XIE J.; LIN, M.; YING, L.; PANG, P.; JI, W. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology, v. 296, p. 115-117, 2020. DOI: https://doi.org/10.1148/radiol.2020200432

BERNHEIM, A.; MEI, X.; HUANG, M.; YANG, Y.; FAYAD, Z.A.; ZHANG, N.; DIAO, K.; LIN, B.; ZHU, X.; LI, K.; LI, S.; SHAN, H.; JACOBI, A.; CHUNG, M. Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology, v. 295, p. 686-691, 2020. DOI: https://doi.org/10.1148/radiol.2020200463

SIMPSON, S.; KAY, F.U.; ABBARA, S.; BHALLA, S.; CHUNG, J.H.; CHUNG, M.; HENRY, T.S.; KANNE, J.P.; KLIGERMAN, S.; KO, J.P.; LITT, H.; Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA - Secondary Publication. Journal of Thoracic Imaging, v. 35, p. 219-227, 2020. DOI: https://doi.org/10.1097/RTI.0000000000000524

GRANDO, R.D.; BRENTANO, V.B.; ZANARDO, A.P.; HERTZ, F.T.; JÚNIOR, L.C.A.; PRIETTO DOS SANTOS, J.F.; GALVÃO, G.S.; ZAVASCKI, A.P.; GAZZANA, M.B. Clinical usefulness of tomographic standards for COVID-19 pneumonia diagnosis: Experience from a Brazilian reference center. Brazilian Journal of Infectious Diseases, v. 24, p. 524-533, 2020. DOI: https://doi.org/10.1016/j.bjid.2020.10.002

MOGAMI, R.; Lopes, A.J.; ARAÚJO FILHO, R.C.; DE ALMEIDA, F.C.S.; MESSEDER, A.M.D.C.; KOIFMAN, A.C.B.; GUIMARÃES, A.B.; MONTEIRO, A. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Radiologia Brasileira [online], v. 54, p. 1-8, 2021. DOI: https://doi.org/10.1590/0100-3984.2020.0133

BIKDELI, B.; MADHAVAN, M.V.; JIMENEZ, D.; CHUICH, T.; DREYFUS, I.; DRIGGIN, E.; NIGOGHOSSIAN, C.; AGENO, W.; MADJID, M.; GUO, Y.; TANG, L.V.; HU, Y.; GIRI, J.; CUSHMAN, M.; QUÉRÉ, I.; DIMAKAKOS, E.P.; GIBSON, C.M.; LIPPI, G.; FAVALORO, E.J.; FAREED, J.; CAPRINI, J.A.; TAFUR, A.J.; BURTON, J.R.; FRANCESE, D.P.; WANG, E.Y.; FALANGA, A.; MCLINTOCK, C.; HUNT, B.J.; SPYROPOULOS, A.C.; BARNES, G.D.; EIKELBOOM, J.W.; WEINBERG, I.; SCHULMAN, S.; CARRIER, M.; PIAZZA, G.; BECKMAN, J.A.; STEG, P.G.; STONE, G.W.; ROSENKRANZ, S.; GOLDHABER, S.Z.; PARIKH, S.A.; MONREAL, M.; KRUMHOLZ, H.M.; KONSTANTINIDES, S.V.; WEITZ, J.I.; LIP, G.Y.H.; Global COVID-19 Thrombosis Collaborative Group; Endorsed by the ISTH, NATF, ESVM, and the IUA; Supported by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. Journals of the American College of Cardiology, v. 75, p. 2950-2973, 2020. DOI: https://doi.org/10.1016/j.jacc.2020.04.031

SUH, Y. J.; HONG, H.; OHANA, M.; BOMPARD, F.; REVEL, M. P.; VALLE, C.; GERVAISE, A.; POISSY, J.; SUSEN, S.; HÉKIMIAN, G.; ARTIFONI, M.; PERIARD, D.; CONTOU, D.; DELALOYE, J.; SANCHEZ, B.; FANG, C.; GARZILLO, G.; ROBBIE, H.; YOON, S. H. Pulmonary Embolism and Deep Vein Thrombosis in COVID-19: A Systematic Review and Meta-Analysis. Radiology, v. 298, p. 70-80, 2021. DOI: https://doi.org/10.1148/radiol.2020203557

OUDKERK, M.; KUIJPERS, D.; OUDKERK, S.F.; VAN BEEK, E.J. The vascular nature of COVID-19. British Journal of Radiology, v. 93, 2020. DOI: https://doi.org/10.1259/bjr.20200718

ZIELESKIEWICZ, L.; MARKARIAN, T.; LOPEZ, A.; TAGUET, C.; MOHAMMEDI, N.; BOUCEKINE, M.; BAUMSTARCK, K.; BESCH, G.; MATHON, G.; DUCLOS, G.; BOUVET, L.; MICHELET, P.; ALLAOUCHICHE, B.; CHAUMOÎTRE, K.; DI BISCEGLIE, M.; LEONE, M; AZUREA Network. Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia. Intensive Care Medicine, v. 46, p. 1707-1713, 2020. DOI: https://doi.org/10.1007/s00134-020-06186-0

TUNG-CHEN, Y.; MARTÍ DE GRACIA, M.; DÍEZ-TASCÓN, A.; ALONSO-GONZÁLEZ, R.; AGUDO-FERNÁNDEZ, S.; PARRA-GORDO, M.L.; OSSABA-VÉLEZ, S.; RODRÍGUEZ-FUERTES, P.; LLAMAS-FUENTES, R. Correlation between Chest Computed Tomography and Lung Ultrasonography in Patients with Coronavirus Disease 2019 (COVID-19). Ultrasound in Medicine and Biology, v. 46, p. 2918-2926, 2020. DOI: https://doi.org/10.1016/j.ultrasmedbio.2020.07.003

LEE, E.; KRAJEWSKI, A.; CLARKE, C.; O'SULLIVAN, D.; HERBST, T.; LEE, S. Arterial and venous thromboembolic complications of COVID-19 detected by CT angiogram and venous duplex ultrasound. Emergency Radiology, v. 28, p. 469-476, 2021. DOI: https://doi.org/10.1007/s10140-020-01884-0

BUONSENSO, D.; RAFFAELLI, F.; TAMBURRINI, E.; BIASUCCI, D.G.; SALVI, S.; SMARGIASSI, A.; INCHINGOLO, R.; SCAMBIA, G.; LANZONE, A.; TESTA, A.C.; MORO, F. Clinical role of lung ultrasound for diagnosis and monitoring of COVID-19 pneumonia in pregnant women. Ultrasound in Obstetrics & Gynecology, v. 56, p. 106-109, 2020. DOI: https://doi.org/10.1002/uog.22055

MUSOLINO, A.M.; SUPINO, M.C.; BUONSENSO, D.; FERRO, V.; VALENTINI, P.; MAGISTRELLI, A.; LOMBARDI, M.H.; ROMANI, L.; D'ARGENIO, P.; CAMPANA, A; Roman Lung Ultrasound Study Team for Pediatric COVID-19 (ROMULUS COVID Team). Lung Ultrasound in Children with COVID-19: Preliminary Findings. Ultrasound in Obstetrics & Gynecology, v. 46, p. 2094-2098, 2020. DOI: https://doi.org/10.1016/j.ultrasmedbio.2020.04.026

FALGARONE, G.; PAMOUKDJIAN, F.; CAILHOL, J.; GIOCANTI-AUREGAN, A.; GUIS, S.; BOUSQUET, G.; BOUCHAUD, O.; SEROR, O. Lung ultrasound is a reliable diagnostic technique to predict abnormal CT chest scan and to detect oxygen requirements in COVID-19 pneumonia. Aging (Albany NY), v. 12, p. 19945-19953, 2020. DOI: https://doi.org/10.18632/aging.104150

JI, L.; CAO, C.; GAO, Y.; ZHANG, W.; XIE, Y.; DUAN, Y.; KONG, S.; YOU, M.; MA, R.; JIANG, L.; LIU, J.; SUN, Z.; ZHANG, Z.; WANG, J.; YANG, Y.; LV, Q.; ZHANG, L.; LI, Y.; ZHANG, J.; XIE, M. Prognostic value of bedside lung ultrasound score in patients with COVID-19. Critical Care, v. 24, p. 700, 2020. DOI: https://doi.org/10.1186/s13054-020-03416-1

MILLINGTON, S.J.; KOENIG, S.; MAYO, P.; VOLPICELLI, G. Lung Ultrasound for Patients With Coronavirus Disease 2019 Pulmonary Disease. Chest, v. 159, p. 205-211, 2021. DOI: https://doi.org/10.1016/j.chest.2020.08.2054

PECORARO, M.; CIPOLLARI, S.; MARCHITELLI, L.; MESSINA, E.; DEL MONTE, M.; GALEA, N.; CIARDI, M.R.; FRANCONE, M.; CATALANO, C.; PANEBIANCO, V. Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19. La Radiologia Medica, v. 126, p. 1273-1281, 2021. DOI: https://doi.org/10.1007/s11547-021-01390-4

SHCHENDRYGINA, A.; NAGEL, E.; PUNTMANN, V.O.; VALBUENA-LOPEZ, S. COVID-19 myocarditis and prospective heart failure burden. Expert Review of Cardiovascular Therapy, v. 19, p. 5-14, 2021. DOI: https://doi.org/10.1080/14779072.2021.1844005

WU, Y.; XU, X.; CHEN, Z.; DUAN, J.; HASHIMOTO, K.; YANG, L.; LIU C.; YANG, C. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain, Behavior, and Immunity, v. 87, p. 18-22, 2020. DOI: https://doi.org/10.1016/j.bbi.2020.03.031

GULKO, E.; OLEKSK, M.L.; GOMES, W.; ALI, S.; MEHTA, H.; OVERBY, P.; AL-MUFTI, F.; ROZENSHTEIN, A. MRI Brain Findings in 126 Patients with COVID-19: Initial Observations from a Descriptive Literature Review. American Journal of Neuroradiology, v. 41, p. 2199-2203, 2020. DOI: https://doi.org/10.3174/ajnr.A6805

ARAGÃO, M.F.V.V.; LEAL, M.C.; CARTAXO FILHO, O.Q.; FONSECA, T.M.; VALENÇA, M.M. Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI. American Journal of Neuroradiology, v. 41, p. 1703-1706, 2020. DOI: https://doi.org/10.3174/ajnr.A6675

CAPITANIO, S.; NORDIN, A.J.; NORAINI, A.R.; ROSSETTI, C. PET/CT in nononcological lung diseases: current applications and future perspectives. European Respiratory Review, v. 25, p. 247-58, 2016. DOI: https://doi.org/10.1183/16000617.0051-2016

JONES, H.A.; MARINO, P.S.; SHAKUR, B.H.; MORRELL, N.W. In vivo assessment of lung inflammatory cell activity in patients with COPD and asthma. European Respiratory Journal, v. 21, p. 567-73, 2003. DOI: https://doi.org/10.1183/09031936.03.00048502

MAUREA, S.; MAINOLFI, C.G.; BOMBACE, C.; ANNUNZIATA, A.; ATTANASIO, L.; PETRETTA, M.; DEL VECCHIO, S.; CUOCOLO, A.; FDG-PET/CT imaging during the Covid-19 emergency: a southern Italian perspective. European Journal of Nuclear Medicine and Molecular Imaging, v. 47, p. 2691-2697, 2020 DOI: https://doi.org/10.1007/s00259-020-04931-7

COSMA, L;. SOLLAKU, S.; FRANTELLIZZI, V.; DE VINCENTIS, G.; Early 18 F-FDG PET/CT in COVID-19. Journal of Medical Imaging and Radiation Oncology, v. 64, p. 671-673, 2020. DOI: https://doi.org/10.1111/1754-9485.13099

DONG, D.; TANG, Z.; WANG, S.; HUI, H.; GONG, L.; LU, Y.; XUE, Z.; LIAO, H.; CHEN, F.; YANG, F.; JIN, R.; WANG, K.; LIU Z.; WEI, J.; MU, W.; ZHANG, H.; JIANG, J.; TIAN, J.; LI, H. The Role of Imaging in the Detection and Management of COVID-19: A Review. IEEE Reviews In Biomedical Engineering, v. 14, p. 16-29, 2021. DOI: https://doi.org/10.1109/RBME.2020.2990959

LÜTJE, S.; MARINOVA, M.; KÜTTING, D.; ATTENBERGER, U.; ESSLER, M.; BUNDSCHUH, R.A. Nuclear medicine in SARS-CoV-2 pandemia: 18F-FDG-PET/CT to visualize COVID-19. Nuklearmedizin, v. 59, p. 276-280, 2020. DOI: https://doi.org/10.1055/a-1152-2341

SETTI, L.; KIRIENKO, M.; DALTO, S.C.; BONACINA, M.; BOMBARDIERI, E. FDG-PET/CT findings highly suspicious for COVID-19 in an Italian case series of asymptomatic patients. European Journal of Nuclear Medicine and Molecular Imaging, v. 47, p. 1649-1656, 2020. DOI: https://doi.org/10.1007/s00259-020-04819-6

ALBANO, D.; BERTAGNA, F.; BERTOLI, M.; BOSIO, G.; LUCCHINI, S.; MOTTA, F.; PANAROTTO, M.B.; PELI, A.; CAMONI, L.; BENGEL, FM.; GIUBBINI, R. Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region. Journal of Nuclear Medicine, v. 61, p. 632-636, 2020. DOI: https://doi.org/10.2967/jnumed.120.246256

SCARLATTEI, M.; BALDARI, G.; SILVA, M.; BOLA, S.; SAMMARTANO, A.; MIGLIARI, S.; GRAZIANI, T.; CIDDA, C.; SVERZELLATI, N.; RUFFINI, L. Unknown SARS-CoV-2 pneumonia detected by PET/CT in patients with cancer. Tumori, v. 106, p. 325-332, 2020. DOI: https://doi.org/10.1177/0300891620935983

DIETZ, M.; CHIRONI, G.; CLAESSENS, Y.E.; FARHAD, R.L.; ROUQUETTE, I.; SERRANO, B.; NATAF, V.; HUGONNET, F.; PAULMIER, B.; BERTHIER, F.; KEITA-PERSE, O.; GIAMMARILE, F.; PERRIN, C.; FARAGGI, M; MONACOVID Group. COVID-19 pneumonia: relationship between inflammation assessed by whole-body FDG PET/CT and short-term clinical outcome. European Journal of Nuclear Medicine and Molecular Imaging, v. 48, p. 260-268, 2021. DOI: https://doi.org/10.1007/s00259-020-04968-8

POLVERARI, G.; ARENA, V.; CECI, F.; PELOSI, E.; IANNIELLO, A.; POLI, E.; SANDRI, A.; PENNA, D. 18F-Fluorodeoxyglucose Uptake in Patient With Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (Coronavirus Disease 2019) Referred to Positron Emission Tomography/Computed Tomography for NSCLC Restaging. Journal of Thoracic Oncology, v. 15, p. 1078-1080, 2020. DOI: https://doi.org/10.1016/j.jtho.2020.03.022

ZOU, S.; ZHU, X. FDG PET/CT of COVID-19. Radiology, v. 296, p. 118, 2020. DOI: https://doi.org/10.1148/radiol.2020200770

SOLLINI, M.; CICCARELLI, M.; CECCONI, M.; AGHEMO, A.; MORELLI, P.; GELARDI, F.; CHITI, A. Vasculitis changes in COVID-19 survivors with persistent symptoms: an [18F]FDG-PET/CT study. European Journal of Nuclear Medicine and Molecular Imaging, v. 48, p. 1460-1466, 2021. DOI: https://doi.org/10.1007/s00259-020-05084-3

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Published

2022-12-20

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Medical imaging technologies applied to the COVID-19 context. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 10, n. 4, p. 1–16, 2022. DOI: 10.15392/2319-0612.2022.2060. Disponível em: https://bjrs.org.br/revista/index.php/REVISTA/article/view/2060.. Acesso em: 21 nov. 2024.

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