Desenvolvimento de protocolos de dosimetria interna empregando o código MCNPx e fantomas voxelizados de referência da ICRP 110
DOI:
https://doi.org/10.15392/bjrs.v5i1.243Keywords:
Internal Dosimetry, MCNPx, ValidationAbstract
The objective of this work was to develop and validate Internal Dosimetry Protocols (IDP) using the ICRP 110 reference voxelized phantoms (RCP_AF and RCP_AM). The reference phantoms were implemented to run on MCNPx. Biodistribution data of 18F-FDG radiopharmaceutical provided in ICRP 106 were used in the simulations. The organs average absorbed doses and the effective committed doses were calculated for each model. The values obtained were compared with two reference works available in the literature for validation purposes. The means of the difference of our values and Zankl et al, 2012 reference values (RV) were 0.1% for RCP_AM and -0.8% for RCP_AF. Considering Hadid et al., 2013 RV, the means of the deviation were -2.5% and -2.6% for RCP_AM and RCP_AF respectively. No statistically significant differences were observed (p <0.01) between the reference values and the values calculated by the IDP developed by our group. Considering this validation designed to estimate the effective dose induced by 18F-FDG injection, internal dosimetry protocols developed by our group have produced suitable dosimetry data.
- Views: 191
- PDF Downloads: 151
Downloads
References
ICRP Publication 110. Adult Reference Computational Phantoms. Ann ICRP, v. 39(2), p. 1-166, 2009.
ICRP Publication 103. The 2007 Recommendations of the International Commission on Ra-diological Protection. Ann ICRP, v. 37(2-4), p. 1-332, 2007.
ICRP Publication 133. The ICRP Computational Framework for Internal Dose Assessment for Reference Adults: Specific Absorbed Fractions. Ann. ICRP, v.45(2), p.1-73, 2016.
TRINDADE, B. M.; CAMPOS, T. P. R. Sistema computacional para dosimetria de nêutrons e fótons baseado em métodos estocásticos aplicado a radioterapia e radiologia. Radiol Bras, v. 44(2), p. 109-116, 2011.
MENDES, B. M.; ALMEIDA, I. G.; TRINDADE, B. M.; CAMPOS, T. P. R. A female voxel phantom for radiopharmaceuticals internal dosimetry [resumo]. In: 4th International Nuclear Chemistry Congress; 2014, Maresias - SP - Brasil. 4th INCC - Abstract Book, p. 1-345, 2014.
MENDES, B. M.; FONSECA, T. C. F.; ALMEIDA, I.G.; TRINDADE, B. M.; CAMPOS T. P. R. Validation of Internal Dosimetry Protocols based in stochastic method. In: International Nuclear Atlantic Conference - INAC 2015; 2015, São Paulo, SP, Brazil.
PAIVA, F. G.; OLIVEIRA, A. H.; MENDES, B. M.; PINTO, J. R.; FILHO, N. A. N.; DANTAS, B. M.; DANTAS, A. L. A.; SILVA, T.A.; LACERDA, M. A. S.; FONSECA, T. C. F. Improvement of the WBC calibration of the Internal Dosimetry Laboratory of the CDTN/CNEN using the physical phantom BOMAB and MCNPX Code. Appl Radiat Isot, v.117, p. 26-30, 2015.
ZANKL, M.; SCHLATTL, H.; PETOUSSI-HENSS, N.; HOESCHEN, C. Electron specific absorbed fractions for the adult male and female ICRP/ICRU reference computational phantoms. Phys Med Biol, v. 57, p. 4501–4526, 2012.
HADID, L.; GARDUMI, A.; DESBRÉE, A. Evaluation of absorbed and effective doses to patients from radiopharmaceuticals using the ICRP 110 reference computational phantoms and ICRP 103 formulation. Radiat Prot Dosimetry, v. 156(2), p. 141–159, 2013.
PELOWITZ, D. B., ed. MCNPXTM User’s Manual - Version 2.7.0. LA-CP-11-00438, 2011. 645p.
ICRP Publication 107. Nuclear Decay Data for Dosimetric Calculations. Ann ICRP, v. 38(3), p. 1-96, 2008.
ICRP Publication 106. Radiation Dose to Patients from Radiopharmaceuticals. A third amendment to ICRP Publication 53. Ann ICRP, v. 38(1-2), p.1-198, 2008.
RAYNAERT, N.; PALMANS, H.; THIERENS, H.; JERAJ, R. Parameter dependence of the MCNP electron transport in determining dose distributions. Med Phys, v. 29(10), p. 2446-2454, 2002.
Published
How to Cite
Issue
Section
License
Licensing: The BJRS articles are licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
